Muscle Strength Science Abstracts

1. Neuromuscul Disord. 2003 Aug;13(6):479-84.

Modification of the functional capacity of sarcoplasmic reticulum membranes in patients suffering from chronic fatigue syndrome

Fulle S, Belia S, Vecchiet J, et al.

Source

Laboratorio Interuniversitario di Miologia, Università ‘G. d’Annunzio’, Nuovo Polo Didattico, 66013 Chieti Scalo, Italy. s.fulle@unich.it

Abstract

This study identifies sarcoplasmic reticulum abnormalities in chronic fatigue syndrome patients, suggesting oxidative modifications impair excitation-contraction coupling. Findings include deregulation of pump activities (Na+/K+ and Ca2+-ATPase) and altered ryanodine channel functioning, contributing to characteristic fatigue.

2. Acta Physiol Scand. 2002 Nov;176(3):227-32.

Altered sarcoplasmic reticulum function in rat diaphragm after high-intensity exercise

Matsunaga S, Inashima S, et al.

Source

Institute of Health Sciences and Physical Education, Osaka City University, Osaka-shi, Osaka, Japan.

Abstract

High-intensity exercise impairs sarcoplasmic reticulum (SR) function in rat diaphragm, decreasing Ca2+ uptake and release rates. These changes, coupled with reduced ATPase activity, suggest that SR dysfunction contributes to fatigue and reduced physical performance.

3. J Appl Physiol. 2002 Mar;92(3):912-22.

Effects of fatigue and training on sarcoplasmic reticulum Ca(2+) regulation in human skeletal muscle

Li JL, Wang XN, et al.

Source

School of Human Movement, Recreation and Performance, Victoria University of Technology, Melbourne, Victoria, Australia.

Abstract

This study compares sarcoplasmic reticulum function across untrained controls, endurance-trained, and resistance-trained athletes. Fatigue significantly reduces Ca2+ regulation, highlighting the role of SR in exercise performance and muscle fiber type dependency.

4. Acta Physiol Scand. 2004 Feb;180(2):195-208.

Effects of prolonged exercise and recovery on sarcoplasmic reticulum Ca2+ cycling properties in rat muscle homogenates

Schertzer JD, Green HJ, et al.

Source

Department of Kinesiology, University of Waterloo, Ontario, Canada.

Abstract

Prolonged exercise and recovery modulate sarcoplasmic reticulum function in rat muscles, with passive recovery yielding greater enhancements in Ca2+-cycling properties. Findings suggest SR adaptations contribute to recovery efficiency.

5. Can J Appl Physiol. 2004 Jun;29(3):308-29.

The sarcoplasmic reticulum in muscle fatigue and disease: role of the sarco(endo)plasmic reticulum Ca2+-ATPase

Tupling AR.

Source

Department of Kinesiology, University of Waterloo, Ontario, Canada.

Abstract

This review explores the role of sarco(endo)plasmic reticulum Ca2+-ATPase in muscle fatigue and disease. Altered SR Ca2+ cycling is identified as a critical factor in muscle dysfunction during repetitive contraction and prolonged fatigue.

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